What is the most important information I should know about oritavancin?
Tell your doctor if you use other medicines or have other medical conditions or allergies.
What is oritavancin?
Oritavancin is an antibiotic that is used to treat severe skin infections caused by bacteria.
Oritavancin may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before receiving oritavancin?
You should not receive oritavancin if you are allergic to it, or if you will be using "unfractionated" heparin within 5 days after your receive oritavancin injection.
Tell your doctor if you have ever had:
- an allergic reaction to medicines such as dalbavancin, telavancin, or vancomycin; or
- if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.
Tell your doctor if you are pregnant or breastfeeding.
Oritavancin is not approved for use by anyone younger than 18 years old.
How is oritavancin given?
Oritavancin is injected into a vein by a healthcare provider, usually as a single dose.
This medicine is injected slowly over 3 hours.
Call your doctor promptly if your symptoms do not improve after receiving oritavancin.
Oritavancin can affect the results of certain medical tests for up to 5 days after your injection. Tell any doctor who treats you that you have been treated with oritavancin.
What happens if I miss a dose?
Since oritavancin is given in a single dose, it does not have a daily dosing schedule.
What should I avoid after receiving oritavancin?
Avoid taking anti-diarrhea medicine without first asking your doctor. Diarrhea may be a sign of a new infection.
For at least 5 days after receiving oritavancin, avoid using heparin.
What are the possible side effects of oritavancin?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel warm, itchy, dizzy, light-headed, sweaty, or have chills, tremors, chest pain, back pain, a rash, or redness in your face or upper body.
Call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after you receive oritavancin); or
- pain, tenderness, redness, swelling, or warmth anywhere in your body.
Common side effects may include:
- nausea, vomiting, diarrhea;
- fever, chills;
- headache; or
- skin infections.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect oritavancin?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Tell your doctor about all your other medicines, especially:
- a blood thinner such as heparin or warfarin (Coumadin, Jantoven).
This list is not complete. Other drugs may affect oritavancin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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